Molecular Formula | C31H38O17 |
Molar Mass | 682.63 |
Density | 1.55±0.1 g/cm3 (20 ºC 760 Torr) |
Boling Point | 917.3±65.0 °C(Predicted) |
Specific Rotation(α) | -20.5 (c, 1.52 in MeOH) |
Solubility | Soluble in water, DMSO, methanol |
Appearance | White powder |
pKa | 8.13±0.15(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Easily absorbing moisture |
In vitro study | Tenuifoliside A (6-30 μM; 24 hours) increases the C6 cells viability significantly by concentration dependent manner. But the viability of the 60 μM treatment group is suppressed. Only 60 μM TFSA induced the release of LDH, shows a toxic effect. Tenuifoliside A (10 μM; 2, 5, 7, 10, 15, 30, 45 and 60 mins) elicits a rapid (starting at 2 min) and marked induction of ERK1/2 phosphorylation peaking at 5 min. And,the enhanced levels of phospho-ERK induced by TFSA are partially blocked by ERK inhibitor U0126. |
Reference Show more | 1. Chen Ying, Yu Pengxin, Ding Hui, Jing Yao Yao, Zhang Lijuan, Yu river water, Yang Jianhui, Song Xinbo, Li Zheng. Study on the content changes of nine index components under the condition of different temperature and high pressure steam sterilization of the classic prescription Kaixin powder [J]. Chinese herbal medicine, 2021,52(04):976-981. 2. [IF = 6.558] Qing Qing Song et al."Binary code, a flexible tool for diagnostic medicinal sequencing of medical plants." Anal Chim Acta. 2019 Dec;1088:89 3. Ruimei Lin et al. [IF = 3.935]. "Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectroscopy and gas chromatography-mass spectroscopy." J Pharmaceut Biomed. 2021 Nov;206 |